MYO5A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA124947

Catalog No. PIPA124947

Description

PA1-24947 detects MYO5A from rat and chicken samples. PA1-24947 will not react with mouse. PA1-24947 has been successfully used in Western blot procedures. The PA1-24947 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues 1782-1799 of chicken MYO5A.

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: MYO5A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q02440, Q9QYF3
• Gene Symbols: MYO5A
• Immunogen: Synthetic peptide, conjugated to KLH, corresponding to residues 1782-1799 of chicken MYO5A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Chicken, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Gene: Myo5a
• Gene Alias: GS1, MYH12, MYO5, MYR12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25017, 396237
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid