MYSM1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524019
DescriptionMetalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
|KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human MYSM1|
|Antigen affinity chromatography|
|Flow Cytometry, Western Blot|
|PBS with 0.09% sodium azide|
|2A-DUB, 2ADUB, RP4-592A1.1, histone H2A deubiquitinase MYSM1, myb-like, SWIRM and MPN domain-containing protein 1|
|-20° C, Avoid Freeze/Thaw Cycles|
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