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NALP11 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523348

Catalog No. PIPA523348


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Description

Description

NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain. Reports suggest that it is a short NALP involved in inflammation potential. NALP proteins are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes. The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1. It is involved in interaction with PYCARD.
Specifications

Specifications

NALP11
Polyclonal
Unconjugated
NLRP11
Liquid
NLRP11
Synthetic peptide (467 PNYLIPSGSREYKEKRE 483) of NALP11 protein.
Protein A
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P59045
CLR19.6, NALP11, NOD17, PAN10, PYPAF6, PYPAF7, NACHT, LRR and PYD containing protein 11, NACHT, LRR and PYD domains-containing protein 11, NACHT, leucine rich repeat and PYD containing 11, PAAD- and NACHT-containing protein 10, PAAD- and NACHT-containing protein 10B, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6, nucleotide-binding oligomerization domain protein 17, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
204801
Documents
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