NALP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521021
A suggested positive control is mouse brain tissue lysate. PA5-21021 can be used with blocking peptide PEP-1135.NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombit NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
|A 14 amino acid peptide near the carboxy terminus of human NALP5.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|CLR19.8, MATER, NALP5, PAN11, PYPAF8; NACHT, LRR and PYD domains-containing protein 5; NACHT, leucine rich repeat and PYD containing 5; mater protein homolog; maternal antigen that embryos require; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|126206, 23968, 308325|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok