NALP8 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521024
A suggested positive control is human colon tissue lysate. PA5-21024 can be used with blocking peptide PEP-1138.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
|A 16 amino acid peptide near the amino terminus of human NALP8.|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|CLR19.2, NALP8, NOD16, PAN4; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-containing protein 8; NACHT, leucine rich repeat and PYD containing 8; PYRIN and NACHT-containing protein 4; nucleotide-binding oligomerization domain protein 16; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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