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NAMPT Rabbit anti-Chicken, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523198

Catalog No. PIPA523198


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Description

Description

NAMPT is a 491 amino acid adipokine belonging to the NAPRTase family. It promotes angiogenesis via activation of the mitogen-activated protein kinase ERK-dependent pathway, is upregulated in neutrophils by IL-1beta, and functions as a novel inhibitor of apoptosis in response to a variety of inflammatory stimuli. It acts as a regulator of NAD+-dependent reactions in smooth muscle cells (SMCs) and in the pathogenesis of type 2 diabetes mellitus. NAMPT plays a role in insulin resistance and markers of hyperandrogenism in lean PCOS patients. It is a longevity protein that can add stress-resistant life to human smooth muscle cells by optimizing SIRT1-mediated p53 degradation. The expression level of NAMPT is high in visceral fat and serum levels in overweight and obese subjects with metabolic syndrome. It is expressed in large amounts in bone marrow, liver tissue, muscle, heart, placenta, lung and kidney tissues.
Specifications

Specifications

NAMPT
Polyclonal
whole serum with 50% glycerol and 0.025% sodium azide
P43490, Q99KQ4, Q80Z29
1110035O14Rik, PBEF, PBEF1, VF, VISFATIN, NAmPRTase, pre-B cell-enhancing factor, pre-B-cell colony enhancing factor 1, pre-B-cell colony-enhancing factor 1
Rabbit
IgG
RUO
Antibody
Polyclonal
Chicken, Human, Mouse, Non-human primate, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
NAMPT
Liquid
NAMPT
Synthetic peptide (39 CREKKTENSKLRKVKYE 55) of NAMPT/Visfatin protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10135, 297508, 417707, 59027
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