NANOS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520553
A suggested positive control is rat brain tissue lysate. PA5-20553 can be used with blocking peptide PEP-0673.os is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, os represses apoptosis during development to ensure proper germ-line development. Unlike os1 whose expression in mice is dispensable, the os2 and os3 proteins are required for germ cell development. os2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while os3-null PGCs are lost during the migration stage regardless of sex. os2 and os3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of os2 can at least partially replace os3 function in a os3-null background. os3 expression can not rescue os2-null defects. This os2 antibody will not cross-react with either os 1 or os3.
|A 13 amino acid peptide near the amino terminus of the human os2.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|NOS2; NOS-2; os homolog 2|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|339345, 365213, 378430|
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