NBS1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522972
Suggested positive control: antigen standard for NBN (transient overexpression lysate), HeLa whole cell extract.The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
|Synthetic peptide made to an internal portion of the mouse protein (within residues 350-400).|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 30% glycerol and 0.1% sodium azide|
|AT-V1, AT-V2, ATV, NBS, NBS1, P95, Nijmegen breakage syndrome 1 (nibrin), cell cycle regulatory protein p95, p95 protein of the MRE11/RAD50 complex|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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