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NBS1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522975

Catalog No. PIPA522975


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Description

Description

Suggested positive control: antigen standard for NBN (transient overexpression lysate), HeLa whole cell extract.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
Specifications

Specifications

NBS1
Polyclonal
Unconjugated
NBN
Liquid
NBN
Synthetic peptide made to an internal portion of the mouse protein (within residues 150-200).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.48 mg/mL
PBS with 30% glycerol and 0.1% sodium azide
O60934, Q9R207
AT-V1, AT-V2, ATV, NBS, NBS1, P95, Nijmegen breakage syndrome 1 (nibrin), cell cycle regulatory protein p95, p95 protein of the MRE11/RAD50 complex
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
27354, 4683
Documents
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