NCALD Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523997
This antibody is predicted to react with bovine, chicken, porcine, non-human primate, rat and Xenopus based on sequence homology.NCALD encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
|PBS with 0.09% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human NCALD|
|Antigen affinity chromatography|
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