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Nebulin Mouse anti-Human, Clone: 1F4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519423

Catalog No. PIMA519423


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Description

Description

Peptide Sequence: NTKTSYHTPA DMLSVTAAKD AQANITNTNY KHLIHKYILL PDAMNIELTR NMNRIQSDNE YKQDYNEWYK GLGWSPAGSL EVEKAKKATE YASDQKYRQH PSNFQFKKLT

This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.
Specifications

Specifications

Nebulin
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
P20929
DKFZp686C1456, FLJ11505, FLJ36536, FLJ39568, FLJ39584, NEB177D, NEM2
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
4703
ELISA, Western Blot
1F4
Unconjugated
NEB
Liquid
NEB
NEB (NP_004534, 2108 a.a. ∽ 2217 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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