NEK3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528569
PA5-28569 targets NEK3 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28569 immunogen is recombit fragment corresponding to a region within amino acids 1 and 255 of Human NEK3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
|Recombit fragment corresponding to a region within amino acids 1 and 255 of Human NEK3|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|HSPK36, HSPK 36, glycogen synthase A kinase, hydroxyalkyl-protein kinase, never in mitosis A-related kinase 3, nimA-related protein kinase 3, phosphorylase B kinase kinase, serine/threonine-protein kinase Nek3|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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