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PPP1R9A Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3064

Catalog No. PA3064

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Neurabin I is a brain-specific protein which contains an F-actin binding domain, a PDZ domain, a transmembrane-protein-interacting-domain, and a coiled-coil region. As its structure suggests, neurabin I is a promiscuous protein binding to F-actin, protein phosphatase 1, TGN38, and p70 S6 kinase. Found exclusively in brain, this protein is highly concentrated in the synapse and has also been shown to be enriched in the lamellipodia of the growth cone during neuronal development. Neurabin I appears to be a bridging protein by targeting other proteins to the synapse or by linking membrane proteins to the actin cytoskeleton.

PA3-064 detects neurabin-1 from human and rat cells and tissues.PA3-064 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects an ~123kDa protein representing neurabin-1 from rat brain extract. Immunofluorescence staining of neurabin-1 in in cultured rat hippocampal cells with PA3-064 results in diffuse cytoplasmic staining.PA3-064 antigen is bacterially expressed coiled-coil domain of rat neurabin-1.
Specifications

Specifications

PPP1R9A
Polyclonal
whole serum diluted in PBS with 0.05% sodium azide
Q9ULJ8, O35867
Neural Tissue-Specific F-Actin-Binding Protein-I, PPP1R9A
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Rat
Immunofluorescence, Western Blot
Unconjugated
PPP1R9A
Liquid
PPP1R9A
Bacterially expressed coiled-coil domain of rat neurabin I.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
55607, 84685
Documents
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