anti-Neurofilament, Heavy chain Polyclonal, Thermo Scientific™

Neurofilament, Heavy chain Polyclonal Ab PA1-10016 from Thermo Scientific™ detects Neurofilament, Heavy chain in Bv and Rt samples, and is validated for ICC, IF, IHC and WB

Manufacturer: Invitrogen PA110016

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Catalog No. 01-670-273

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    Specifications

    Antigen Neurofilament, Heavy chain
    Applications Immunocytochemistry,Immunofluorescence,Immunohistochemistry,Western Blot
    Conjugate Unlabeled
    Cross Reactivity Bovine,Rat
    Format Serum
    Formulation 100μL unpurified antibody in whole serum and 10mM sodium azide
    Gene Accession No. P16884
    Gene Alias NFH, NHC, NF 200 kD
    Gene Symbols NEFH
    Host Species Rabbit
    Immunogen Native NF-H purified from bovine spinal cord
    Isotype IgG
    Quantity 100μL
    Species Reactivity Bovine, Rat
    Storage Requirements avoiding freeze/thaw cycles.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 24587, 528842

    Neurofilament, Heavy chain Polyclonal Ab PA1-10016 from Thermo Scientific™ detects Neurofilament, Heavy chain in Bv and Rt samples, and is validated for ICC, IF, IHC and WB

    Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (~70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
    Host Species: Rabbit
    Cross Reactivity: Bovine, Rat
    Isotype: IgG
    Immunogen: Native NF-H purified from bovine spinal cord
    Formulation: 100µL unpurified antibody in whole serum and 10mM sodium azide
    Synonyms: NFH, NHC, NF 200 kD
    Uniprot Accession: P16884
    Entrez GeneID: 24587, 528842
    Gene Symbol: NEFH
    PA1-10016 detects Neurofilament NF-H, primarily the hyperphosphorylated axonal form which yields a band at ~200kDa in Western blot applications.

  • Description & Specifications

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