Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Neurofilament, Medium chain Polyclonal Antibody, Invitrogen™

Neurofilament, Medium chain Antibody, PA1-10015, from Invitrogen™. Species Reactivity: Bv, Ck, Eq, Hu, Ms, Po, Rt; Applications: ELISA, ICC, IF, IHC, WB.

Manufacturer:  Invitrogen PA110015

Catalog No. 01-670-272


  Check Availability
Add to cart

Specifications

Description

Neurofilament, Medium chain Antibody, PA1-10015, from Invitrogen. Species Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat; Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (~70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Rabbit
Cross Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Isotype: IgG
Immunogen: Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
Formulation: 100µL unpurified antibody in whole serum and no preservative
Synonyms: NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Uniprot Accession: O77788, P07197, P08552, P08553, P12839, P16053
Entrez GeneID: 100054129, 100625407, 18040, 24588, 281347, 396206, 4741
Gene Symbol: NEFM
In Western blot, this antibody detects bands at ~145kDa in crude homogenates of rat cerebellum homogenate. Human and bovine run slower at ~160kDa. A minor band at1~110kDa is also frequently seen, which appears to be an in-vivo proteolytic fragment of NF-M.
Description & Specifications

Specifications

Neurofilament, Medium chain
Unlabeled
Serum
O77788, P07197, P08552, P08553, P12839, P16053
NEFM
Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
100μL
avoiding freeze/thaw cycles.
Polyclonal
Bovine,Chicken,Equine,Human,Murine,Porcine,Rat
ELISA,Immunocytochemistry,Immunofluorescence,Immunohistochemistry,Western Blot
Bovine,Chicken,Equine,Human,Mouse,Porcine,Rat
100μL unpurified antibody in whole serum and no preservative
NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Rabbit
IgG
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Primary
100054129, 100625407, 18040, 24588, 281347, 396206, 4741
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit