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Neurogenin 1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511890

Catalog No. PIPA511890


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Description

Description

Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
Specifications

Specifications

Neurogenin 1
Polyclonal
PBS with 0.09% sodium azide
Q92886
NEUROG1
KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Neurogenin1 (NeuroG1)
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
Unconjugated
NEUROG1
Liquid
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4762
Documents
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