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Neurogenin 3 Mouse, Unlabeled, Clone: 7, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610790

Catalog No. BDB610790


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Description

Description

Neurogenins are a family of atonal-related bHLH (basic helix-loop-helix) proteins that have been implicated in vertebrate neurogenesis. Members of this family include Neurogenin 1, 2, and 3. In a search for proteins that control early neuronal development, Neurogenin 1 was identified as a novel, Neuro-D-related bHLH protein that is expressed prior to Neuro-D in mouse and Xenopus. Identification of Neurogenins 2 and 3 defined the Neurogenin family. Analysis indicates that neurogenin gene expression defines progenitor populations in the developing nervous system and that neurogenin proteins and Neuro-D function in a cascade. Neurogenin proteins are expressed prior to Neuro-D and subsequent to another bHLH protein, MASH7. Neurogenin 3 is a 244 amino acid, 23kDa protein that is expressed in fetal, neonatal, and neural tissues, as well as in several neuronal cell lines. Temporal and spatial expression of the neurogenin proteins is critical to proper neural determination and differentiation.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

Specifications

Neurogenin 3
7
Unconjugated
Affinity Purified
Mouse Neurogenin 3 aa. 9-148
50μg
Cell Biology
Primary
Human, Murine, Rat
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Documents
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