NRGN Goat anti-Human, Mouse, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA519209
This antibody is predicted to react with bovine and canine based on sequence homology.Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
|Synthetic peptide sequence (KIKSGERGRKG) corresponding to the internal amino acids of NRGN|
|Antigen affinity chromatography|
|Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|Q92686, P60761, Q04940|
|NRGN; neurogranin (protein kinase C substrate, RC3); RC3; hng; calmodulin-binding protein; neurogranin; protein kinase C substrate|
|-20° C, Avoid Freeze/Thaw Cycles|
|4900, 64011, 64356|
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