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NRGN Goat anti-Human, Mouse, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA519209

Catalog No. PIPA519209


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Description

Description

This antibody is predicted to react with bovine and canine based on sequence homology.

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Specifications

Specifications

NRGN
Polyclonal
Unconjugated
NRGN
Liquid
NRGN
Synthetic peptide sequence (KIKSGERGRKG) corresponding to the internal amino acids of NRGN
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q92686, P60761, Q04940
NRGN; neurogranin (protein kinase C substrate, RC3); RC3; hng; calmodulin-binding protein; neurogranin; protein kinase C substrate
Goat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
4900, 64011, 64356
Documents
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