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Neuroserpin Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528434

Catalog No. PIPA528434


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Description

Description

PA5-28434 targets Neuroserpin in WB applications and shows reactivity with Human samples. The PA5-28434 immunogen is synthetic peptide corresponding to a region within amino acids 349 and 410 of Human Neuroserpin. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a domitly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Specifications

Specifications

Neuroserpin
Polyclonal
Unconjugated
SERPINI1
Liquid
SERPINI1
Synthetic peptide corresponding to a region within amino acids 349 and 410 of Human Neuroserpin
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 10% glycerol and 0.01% thimerosal; pH 7
Q99574
PI12, neuroserpin, PI-12, neuroserpin, peptidase inhibitor 12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1, serpin I1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5274
Documents
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