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Sortilin Sheep anti-Mouse, Rat, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen OSS00052W

Catalog No. PIOSS00052W


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Description

Description

Reconstitute with 100 µL of distilled water.

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
Specifications

Specifications

Sortilin
Polyclonal
whole serum with no preservative
Q6PHU5, O54861
Neurotensin receptor 3, NTR3, Glycoprotein 110, Gp110, Nt3, Nts3
Sheep
IgG
RUO
Antibody
Polyclonal
Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Unconjugated
Sort1
Lyophilized
SORT1
A synthetic peptide from the extracellular, N-terminal part of rat Sortilin
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
20661, 83576
Documents
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