Neurotrypsin Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520363
A suggested positive control is SK-N-SH cell lysate. PA5-20363 can be used with blocking peptide PEP-0483.Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
|A 23 amino acid peptide from near the amino terminus of human neurotrypsin.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|P56730, O08762, G3V801|
|BSSP-3, BSSP3, MRT1; brain-specific serine protease 3; leydin; neurotrypsin|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|19142, 8492, 85266|
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