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NFE2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527762

Catalog No. PIPA527762


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Description

Description

PA5-27762 targets NF-E2 in WB applications and shows reactivity with Human and mouse samples. The PA5-27762 immunogen is recombit fragment corresponding to a region within amino acids 1 and 373 of Human NF-E2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Specifications

Specifications

NFE2
Polyclonal
Unconjugated
NFE2
Liquid
NFE2
Recombit fragment corresponding to a region within amino acids 1 and 373 of Human NF-E2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ChIP assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
1.03 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q16621, Q07279
NF-E2, p45, leucine zipper protein NF-E2, nuclear factor, erythroid-derived 2 45 kDa subunit, p45 NF-E2, transcription factor NF-E2 45 kDa subunit
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18022, 4778
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