NFE2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527762
PA5-27762 targets NF-E2 in WB applications and shows reactivity with Human and mouse samples. The PA5-27762 immunogen is recombit fragment corresponding to a region within amino acids 1 and 373 of Human NF-E2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
|Recombit fragment corresponding to a region within amino acids 1 and 373 of Human NF-E2|
|Antigen affinity chromatography|
|ChIP assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|NF-E2, p45, leucine zipper protein NF-E2, nuclear factor, erythroid-derived 2 45 kDa subunit, p45 NF-E2, transcription factor NF-E2 45 kDa subunit|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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