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NFATC1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141041

Catalog No. 01-676-646


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Description

Description

Suggested positive control: antigen standard for NFATC1 (transient overexpression lysate).

NFAT (nuclear factor of activated T cell transcription factors play critical roles in gene transcription during immune responses. The NFAT complex is made up of NFATc (NFATc1-4) protein and activator protein-1 (AP-1) transcription factor. NFAT proteins are regulated by Ca2+. NFATc1 is a substrate protein phosphatase calcineurin, a critical mediator of calcium signals during T-cell activation.  NFATc1 activation requires the translocation of the transcription factor into the nucleus, a process that is mediated by calcineurin.
Specifications

Specifications

NFATc1
Polyclonal
Unconjugated
NFATC1
Liquid
NFATC1
Synthetic peptide N(263) K R K Y S L N G R Q P P Y S P H H S(282) of human NFaTc1
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.05% sodium azide
O95644, O88942
NFATC1, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, MGC138448, NFAT2, NFATc, NFATC, NF-ATc, NF-ATC, NF-ATc1, NFAT trans
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18018, 4772
Documents
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