NEK7 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA124580
PA1-24580 detects NIMA-Related Kinase 9 in Human samples. PA1-24580 has been successfully used in Immunohistochemistry (paraffin) procedures. PA1-24580 immunogen corresponds to Synthetic peptide - KLH conjugated. Sequence identity/similarity to Mouse: 100/100%.NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.
|Synthetic peptide - KLH conjugated. Sequence identity/similarity to Mouse: 100/100%.
|Never In Mitosis Gene A-Related Kinase 9
|Antigen affinity chromatography
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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