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NIPSNAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520500

Catalog No. PIPA520500


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20500 can be used with blocking peptide PEP-0620.

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
Specifications

Specifications

NIPSNAP1
Polyclonal
Unconjugated
NIPSNAP1
Liquid
NIPSNAP1
An 18 amino acid peptide from near the carboxy terminus of human NIPSNAP.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9BPW8, O55125
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1; protein NipSnap homolog 1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
18082, 360971, 8508
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