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Nkx6.1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523070

Catalog No. PIPA523070

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

NKX6.1 is a bi-functional transcription factor that has effects in both the central nervous system and in the pancreas. It has both expression and repression effects on genes, leading to the proper formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. It is known to interact with Pax6 and Pdx-1, probably at or near the 60 amino acid homeobox DNA-binding domain. Due to its obvious relationship to beta cells and CNS, NKX6.1 is becoming a more interesting target for therapies in diabetes and certain brain diseases.
Specifications

Specifications

Nkx6.1
Polyclonal
Unconjugated
NKX6-1
Liquid
NKX6-1
A synthetic peptide made to an internal region of the human Nkx6.1 protein (within residues 50-200).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
1.0 mg/mL
PBS with 0.05% sodium azide
P78426, Q99MA9
NKX6.1, NKX6A, NK homeo box, family 6, member A, NK homeobox, family 6, A, NK6 transcription factor homolog A, NK6 transcription factor related, locus 1, homeobox protein NK-6 homolog A, homeobox protein Nkx-6.1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18096, 4825
Documents
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