NLRX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521018
A suggested positive control is rat spleen tissue lysate. PA5-21018 can be used with blocking peptide PEP-1132.NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kappa-B and JNK pathways by inducing reactive oxygen species production.
|A 14 amino acid peptide near the amino terminus of human NOD5.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q86UT6, Q3TL44, Q5FVQ8|
|CLR11.3, DLNB26, NOD26, NOD5, NOD9; NLR family, X1; NOD-like receptor X1; caterpiller protein 11.3; nucleotide-binding oligomerization domain protein 26; nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain protein 9; nucleotide-binding oligomerization domain, leucine rich repeat containing X1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|270151, 315599, 79671|
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