Nogo Receptor Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141202
DescriptionNgBR, also known as Nogo-B receptor, is a 293 amino acid rich member of the UPP synthetase family. Though the extact fundtion of NgBR is still not clear, reports suggest that this membrane protein acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. It has similarity with UPP synthetase proteins which suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins but has no lipid transferase activity. NgBR colocalizes with Nogo-B during VEGF and wound healing angiogenesis and is thus able to regulate vascular remodeling and angiogenesis. Nogo-B and NgBR mediate chemotaxis in HUVECs and induced tube formation in three-dimensional cultures.
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|113912, 65078, 65079|
|PBS with 0.05% sodium azide|
|Q9BZR6, Q99PI8, Q99M75|
|Synthetic peptide corresponding to residues 64-74 of human Nogo-B receptor (NgBR).|
|Human, Mouse, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok