Nogo Receptor Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141202
DescriptionNgBR, also known as Nogo-B receptor, is a 293 amino acid rich member of the UPP synthetase family. Though the extact fundtion of NgBR is still not clear, reports suggest that this membrane protein acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. It has similarity with UPP synthetase proteins which suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins but has no lipid transferase activity. NgBR colocalizes with Nogo-B during VEGF and wound healing angiogenesis and is thus able to regulate vascular remodeling and angiogenesis. Nogo-B and NgBR mediate chemotaxis in HUVECs and induced tube formation in three-dimensional cultures.
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|113912, 65078, 65079|
|PBS with 0.05% sodium azide|
|Q9BZR6, Q99PI8, Q99M75|
|Synthetic peptide corresponding to residues 64-74 of human Nogo-B receptor (NgBR).|
|Human, Mouse, Rat|
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