NOR-1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA124536

Catalog No. PIPA124536

Description

PA1-24536 detects NOR-1 in Human samples. PA1-24536 has been successfully used in Immunohistochemistry (paraffin) procedures. PA1-24536 immunogen corresponds to Synthetic peptide - KLH conjugated. Sequence identity/similarity to Mouse: 65/75%. Rat: 65/75%.

NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3′ variant.

Specifications

• Antigen: NOR-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q92570
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8013
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Gene: NR4A3
• Gene Symbols: NR4A3
• Immunogen: Synthetic peptide - KLH conjugated. Sequence identity/similarity to Mouse: 65/75%. Rat: 65/75%.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG