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NOTCH3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513203

Catalog No. PIPA513203


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Description

Description

This antibody is predicted to react with human based on sequence homology.

NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal domit arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Specifications

Specifications

NOTCH3
Polyclonal
Unconjugated
NOTCH3
Liquid
NOTCH3
KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q9UM47, Q61982
Neurogenic locus notch homolog protein 3; Notch 3;
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
18131, 4854
Documents
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