MilliporeSigma anti-NQO1, Polyclonal
Rabbit Polyclonal Antibody
Manufacturer: MilliporeSigma ST1535100UG
Specifically detects NQO1 Clone: in Human, Mouse samples, and it is validated for Immuno BlottingNQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
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|Full-length, recombinant human NQO1 (aa 1-274)|
|Immuno Blotting, Immunoblot|
|In PBS, pH 7.2.|
|Recognizes the ∽30kDa NQO1 protein in human stomach tissue, mouse brain tissue, and HepG2 cells.|
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