Glucocorticoid Receptor Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA524793

Catalog No. PIPA524793

Description

NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.

Specifications

• Antigen: Glucocorticoid Receptor
• Classification: Polyclonal
• Gene: NR3C1
• Gene Alias: GCCR, GCR, GR, GRL, glucocorticoid nuclear receptor variant 1, glucocorticoid receptor, nuclear receptor subfamily 3 group C member 1 variant DL-1, nuclear receptor subfamily 3 group C member 1 variant NS-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2908
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P04150
• Gene Symbols: NR3C1
• Immunogen: KLH conjugated synthetic peptide between 713-742 amino acids from the C-terminal region of human NR3C1
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG