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NOR-1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527372

Catalog No. PIPA527372


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Description

Description

PA5-27372 targets NR4A3 in WB applications and shows reactivity with Human samples. The PA5-27372 immunogen is recombit protein fragment corresponding to a region within amino acids 1 and 139 of Human NR4A3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene.
Specifications

Specifications

NOR-1
Polyclonal
Unconjugated
NR4A3
Liquid
NR4A3
Recombit protein fragment corresponding to a region within amino acids 1 and 139 of Human NR4A3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
0.34 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q92570
CHN, CSMF, MINOR, NOR1, TEC, chondrosarcoma, extraskeletal myxoid, fused to EWS, mitogen-induced nuclear orphan receptor, neuron-derived orphan receptor 1, nuclear hormone receptor NOR-1, nuclear receptor subfamily 4 group A member 3, translocated in extraskeletal chondrosarcoma
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
8013
Documents
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