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NSD2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528409

Catalog No. PIPA528409


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Description

Description

PA5-28409 targets NSD2 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28409 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 44 of Human NSD2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
Specifications

Specifications

NSD2
Polyclonal
Unconjugated
NSD2
Liquid
NSD2
Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human NSD2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
O96028
MMSET, NSD2, REIIBP, TRX5, WHS, IL5 promoter REII region-binding protein, multiple myeloma SET domain containing protein type III, nuclear SET domain-containing protein 2, probable histone-lysine N-methyltransferase NSD2, trithorax/ash1-related protein 5
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
7468
Documents
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