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NUP155 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520564

Catalog No. PIPA520564


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Description

Description

A suggested positive control is P815 cell lysate. PA5-20564 can be used with blocking peptide PEP-0684.

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.
Specifications

Specifications

NUP155
Polyclonal
Unconjugated
NUP155
Liquid
NUP155
An 18 amino acid peptide from near the carboxy terminus of human NUP155.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O75694, Q99P88
N155; 155 kDa nucleoporin; nuclear pore complex protein Nup155; nucleoporin Nup155
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
170762, 9631
Documents
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