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NR4A1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA124400

Catalog No. PIPA124400

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-24400 detects Nurr77 in human samples. PA1-24400 has been successfully used in Western blot and immunohistochemistry procedures. In Western Blots, dilute using a 5% skim milk/PBS buffer solution. The PA1-24400 immunogen is a synthetic peptide corresponding to a region of human NR4A1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Three transcript variants encoding two distinct isoforms have been identified for this gene. Variant (3), also known as TRC beta, contains multiple differences compared to variant 1. The resulting isoform (b) contains a shorter and distinct C-terminus compared to isoform a.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NR4A1
Polyclonal
Unconjugated
P22736
Rabbit
Antigen affinity chromatography
RUO
3164
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
NR4A1
NR4A1
Synthetic peptide corresponding to a region of human NR4A1
50 μg
Primary
Human
Antibody
IgG
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