Thermo Scientific Lab Vision NY-BR-1, Mouse Monoclonal Antibody
Take advantage of a quality product that delivers accurate results with the Thermo Scientific NY-BR-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS1932R7
Take advantage of a quality product that delivers accurate results with the Thermo Scientific NY-BR-1, Mouse Monoclonal Antibody.NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive.
Host Species: Mouse
Clone: NY-BR-1No. 2
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: a 77 aa peptide from human NYBR-1 protein
Molecular Weight: 150-160kDa
Positive Control: Breast carcinoma
Cellular Localization: Predominantly cytoplasmic and occasional nuclear
|a 77 aa peptide from human NYBR-1 protein|
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