Thermo Scientific™ Lab Vision™ NY-BR-1, Mouse Monoclonal Antibody

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ NY-BR-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS1932R7

Catalog No. MS1932R7

Description

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ NY-BR-1, Mouse Monoclonal Antibody.

NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive.

Host Species: Mouse

Clone: NY-BR-1No. 2

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: a 77 aa peptide from human NYBR-1 protein

Molecular Weight: 150-160kDa

Positive Control: Breast carcinoma

Cellular Localization: Predominantly cytoplasmic and occasional nuclear

Recommended for:

Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: NY-BR-1
• Clone: NY-BR-1 No.2
• Host Species: Murine
• Quantity: 7mL
• Primary or Secondary: Primary

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Immunogen: a 77 aa peptide from human NYBR-1 protein
• Type: Primary
• Target Species: Human