OAS3 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA513211
This antibody is predicted to react with mouse and rat based on sequence homology.OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2′,5′-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2′P5′A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
|KLH conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3
|Ammonium sulfate precipitation, Size-exclusion - Dialysis
|-20° C, Avoid Freeze/Thaw Cycles
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