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OCT 4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527438

Catalog No. PIPA527438


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Description

Description

PA5-27438 targets OCT3/4 in FACS, IF, IP, IHC (P), and WB applications and shows reactivity with Human and mouse samples. The PA5-27438 immunogen is recombit fragment corresponding to a region within amino acids 1 and 360 of Human OCT3/4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing ft.s sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Specifications

Specifications

OCT 4
Polyclonal
Unconjugated
POU5F1
Liquid
POU5F1
Recombit fragment corresponding to a region within amino acids 1 and 360 of Human OCT3/4
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.49 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Q01860, P20263
OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4, POU domain transcription factor OCT4, POU domain, class 5, transcription factor 1, POU-type homeodomain-containing DNA-binding protein, octamer-binding protein 3, octamer-binding protein 4, octamer-binding transcription factor 3, octamer-binding transcription f
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18999, 5460
Documents
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