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OCT1 (POU2F1) Rabbit anti-Canine, Equine, Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523392

Catalog No. PIPA523392


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Description

Description

OCT-1, Octamer binding transcription factor 1 binds to an octamer motif (5 ft.-ATTTGCAT-3 ft.) and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes for immunoglobulins. POU domain proteins contain a bipartite DNA-binding domain, which is divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is conferred at the dimerization level. POU dimer from the OCT-1 gene formed on the palindromic OCT factor recognition element, or PORE, could recruit the transcriptional coactivator OBF1. This octamer sequence within immunoglobulin promoters are sufficient for lymphoid-specific promoter activity in lymphoid cells. Oct-1 regulates the expansion and/or maintece of mature B cells. In its absence mature B-cell pull is strongly reduced.
Specifications

Specifications

OCT1 (POU2F1)
Polyclonal
Unconjugated
POU2F1
Liquid
POU2F1
Synthetic peptide (4 CSDYVLDSR 12) of OCTL1/OCT-1 protein.
Protein A
RUO
Antibody
Polyclonal
Canine, Equine, Human, Non-human Primate
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P14859
OCT1, OTF1, oct-1B, NF-A1, OTF-1, Octamer-binding transcription factor-1, POU domain, class 2, transcription factor 1, oct-1, octamer-binding protein 1, octamer-binding transcription factor 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100051363, 490360, 5451
Documents
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