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GPR68 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112713

Catalog No. 01-674-848


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Description

Description

Western blot should be visualized using a high sensitivity secondary/substrate system (i.e SuperSignal West Femto Maximum Sensitivity Substrate). A suggested positive control for this product is OGR1 transfected cell lysate.

OGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing. SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.
Specifications

Specifications

GPR68
Polyclonal
Unconjugated
GPR68
Liquid
GPR68
Recombit protein corresponding to human OGR1 (GPR68) protein.
Protein A/G
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Neutralization, Western Blot
1 mg/mL
PBS with 0.08% sodium azide
Q15743
G Protein-Coupled Receptor OGR1/GPR68
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
8111
Documents
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