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Stathmin 1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520383

Catalog No. PIPA520383


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20383 can be used with blocking peptide PEP-0500.

Op18 belongs to the stathmin family of genes and encodes a ubiquitous cytosolic phosphoprotein that may function as an intracellular relay integrating several signaling pathways such as those involved in cell proliferation and differentiation. Op18 has also been shown to be involved in the regulation of the microtubule filament system by destabilizing microtubules, thereby preventing assembly and promoting the disassembly of microtubules. More recently, op18 has been implicated as a potential target of the ASK1-p38 MAP kinase cascade, suggesting that the ASK1-p38 cascade may regulate microtubule dynamics through op18. Op18 is highly expressed in a wide variety of human maligcies, including leukemia, prostate cancer, ovarian carcinoma, and breast carcinoma, suggesting that op18 may be an ideal target for anti-cancer therapeutics.
Specifications

Specifications

Stathmin 1
Polyclonal
Unconjugated
STMN1
Liquid
STMN1
A 17 amino acid peptide from near the amino terminus of human op18.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P16949, P54227, P13668
RP1-125I3.5, C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN; leukemia-associated phosphoprotein p18; metablastin; oncoprotein 18; phosphoprotein 19; phosphoprotein p19; prosolin; stathmin; stathmin 1/oncoprotein 18; transmembrane protein C1orf215
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
16765, 29332, 3925
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