Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MilliporeSigma™ anti-Opioidµ Receptor (384-398), Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC165L100UL

Catalog No. PC165L100UL

Add to cart



Specifically detects Opioidµ Receptor (384-398) Clone: in Rat samples, and it is validated for Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting

Opioid peptides are endogenous neuromodulators, which have been identified from brain, and play a major role in the nociceptive pathway by interacting with several membrane receptors, defined asµ,,delta;, and,kappa;. These peptides are derived from the cleavage of precursor proteins to produce theβ-endorphin, enkephalin, and dynorphin peptides. Leu-enkephalin, Met-enkephalin, andβ-endorphin all bind theµ and,delta; receptors with high affinity, whileβ-endorphin also exhibits low affinity,kappa; binding. Dynorphin A and dynorphin B both bind the,kappa; receptor with high affinity. In addition to these endogenous peptides, a number of exogenous nonpeptide molecules known as alkaloids or opiates also interact with the receptors to mediate a number of biological events which include the modulation of pain, analgesia, behavior, locomotor activity, and neuroendocrine physiology. Although the,delta; opioid receptor subtype was the first subtype identified, all three receptor classes are G protein-coupled receptors which have been shown to inhibit adenylate cyclase, decrease the conductance of voltage-gated Ca2+ channels, or activate K+ channel current.


Opioidμ Receptor (384-398)
Undiluted Serum
a synthetic peptide corresponding to amino acids 384-398 of rat opioid μ receptor
Immuno Blotting, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Undiluted serum.
Recognizes the ∽44-45kDa opiodμ receptor in caudate putamen and the dorsal horn of the spinal cord.
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only