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Rhodopsin Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen OSR00220W

Catalog No. PIOSR00220W


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Description

Description

Reconstitute with 100 µL of distilled water. Centrifuge to remove any insoluble material.

Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal. Abs(max)=495 nm. Rod shaped photoreceptor cells which mediates vision in dim light. Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region. Defects in RHO are the cause of retinitis pigmentosa type 4 (RP4). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP4 inheritance is autosomal domit. Defects in RHO are also a cause of retinitis pigmentosa autosomal recessive (ARRP). Also, defects in RHO are a cause of autosomal domit congenital stationary night blindness 1 (CSNBAD1); also known as rhodopsin-related congenital stationary night blindness. Congenital stationary night blindness is a nonprogressive retinal disorder characterized by impaired night vision and ocular symptoms such as myopia, hyperopia, nystagmus and reduced visual acuity.
Specifications

Specifications

Rhodopsin
Polyclonal
whole serum with no preservative
P08100, P15409, P51489
Rhodopsin, opsin-2, RHO, OPN2, RP4, MGC138309, MGC138311
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry, Western Blot
Unconjugated
RHO
Lyophilized
RHO
A synthetic peptide from c-terminal region of human Rhodopsin
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
212541, 24717, 6010
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