ORAI2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520369
A suggested positive control is Jurkat cell lysate. PA5-20369 can be used with blocking peptide PEP-0486.Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.
|A 15 amino acid peptide from near the carboxy terminus of human ORAI2.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|PP1729, C7orf19, CBCIP2, MEM142B, TMEM142B; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; H_NH0514P08.8; protein orai-2; putative protein ORAI2-2; transmembrane protein 142B|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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