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ORC4 Mouse anti-Human, Clone: 2A8, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519508

Catalog No. PIMA519508


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Description

Description

Peptide Sequence: MSSRKSKSNS LIHTECLSQV QRILRERFCR QSPHSNLFGV QVQYKHLSEL LKRTALHGES NSVLIIGPRG SGKTMLISHA LKELMEIEEV SENVLQVHLN GLLQINDKIA LKEITRQLNL ENVVGDKVFG SFAENLSFLL EALKKGDRTS SCPVIFILDE FDLFAHHKNQ TLLYNLFDIS QSAQTPIAVI GLTCRLDILE LLEKRVKSRF SHRQIHLMNS FGFPQYVKIF KEQLSLPAEF PDKVFAEK

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and -5L. Three alternatively spliced transcript variants encoding the same protein have been reported.
Specifications

Specifications

ORC4
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
O43929
ORC4L, ORC4P, origin recognition complex subunit 4, origin recognition complex, subunit 4 homolog, origin recognition complex, subunit 4-like
Mouse
IgG2b, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5000
ELISA, Immunocytochemistry, Immunofluorescence
2A8
Unconjugated
ORC4
Liquid
ORC4
orc4 (AAH05388, 1 a.a. ∽ 248 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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