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OVCA2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA15860

Catalog No. 01-675-398


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Description

Description

Chromosome 17 is a hotspot for chromosomal aberrations in breast and ovarian cancer. Candidate oncogenes and tumor suppressors located on this chromosome include OVCA1 and OVCA2, p53, BRCA1, HER2/neu and others. OVCA1 and 2 map to a highly conserved region on human chromosome 17p13.3 that is deleted in 80% of ovarian cancers and shows frequent loss of heterozygosity in breast cancers . OVCA1 is induced by BRCA1 and is closely linked to p53, a well-known tumor suppressor gene. The close linkage of OVCA1 and p53 suggests that coordinated loss of the two genes may lead to ovarian, breast and other tumor types.
Specifications

Specifications

OVCA2
Polyclonal
whole serum with 0.1% sodium azide
Q8WZ82
OVCA2
Human synthetic peptide (aa 27-41) coupled to KLH
50 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
124641
Western Blot
Unconjugated
OVCA2
Liquid
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
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