OXPAT Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA146216
The target sequence has 89% sequence homology with rat and 75% sequence homology with bovine. Suggested positive control: human and mouse heart lysate.OXPAT is a novel PAT-1 protein that is expressed in highly oxidative tissues. Lipid droplet proteins of the PAT family regulate cellular neutral lipid stores. OXPAT is induced by physiological (fasting), pathophysiological (insulin deficiency), pharmacological (peroxisome proliferator-activated receptor [PPAR] agonists), and genetic (muscle-specific PPAR alpha overexpression) disturbances that increase fatty acid utilization. It is suggested that OXPAT is a marker for PPAR activation and fatty acid oxidation. As well, it may contribute to adaptive responses to the fatty acid responsibility that accompanies fasting, insulin deficiency, and overnutrition, responses that are defective in obesity and type 2 diabetes.
|C-terminal region of the mouse OXPAT protein, with in residues 400-463 [UniprotNo. Q8BVZ1].|
|Antigen affinity chromatography|
|PBS with 30% glycerol and 0.1% sodium azide|
|LSDA5, LSDP5, MLDP, OXPAT|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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