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p36/MAT1 Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610532

Catalog No. BDB610532


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Description

Description

Regulation of the cell cycle by cyclin-dependent kinases (cdks) is controlled by the phosphorylation of a conserved threonine residue in their catalytic subunit. Cdks are activated as a result of the phosphorylation of another cyclin-dependent kinase, cdk-activating kinase (CAK). This kinase has two subunits: the catalytic Cdk7 and the regulatory cyclin H. A 36 kDa protein, p36 (also known as Menage A Trois-1 (MAT1)), coimmunoprecipitates with CAK. p36 is a member of the RING finger family of proteins characterized by a C3HC4 zinc-binding domain. p36 functions as a CAK assembly factor and is involved in the regulation of CAK activation.

Specifications

Specifications

p36/MAT1
6
Unconjugated
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50μg
Cell Biology
Monoclonal
Immunofluorescence, Immunoprecipitation, Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Primary
Canine, Chicken, Frog, Human, Murine, Rat
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