Thermo Scientific Lab Vision p53 Ab-6, Mouse Monoclonal Antibody
Achieve accurate, reproducible results with the Thermo Scientific p53 Ab-6, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS187P1
Achieve accurate, reproducible results with the Thermo Scientific p53 Ab-6, Mouse Monoclonal Antibody.p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Host Species: Mouse
Species Reactivity: Human, Monkey and Cow. Reacts weakly with Mouse and Rat. Others not known.
Epitope: aa 11-25
Immunogen: Recombinant human wild-type p53 protein expressed in E. coli
Molecular Weight: 53kDa
Positive Control: SKBR-3 cells or MDA-231 cells, Colon CA
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
- Flow Cytometry
- Gel Supershift Assay
USA: RUO; Int'l: RUO
|Purified Ab with BSA and Azide|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Recombinant human wild-type p53 protein expressed in E. coli|
|Bovine, Human, Non-human Primate|
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